When the Raiders (1-3) travel to face the Chiefs (3-1) to close Week 5 of the 2022 NFL regular season on "Monday Night Football" (8:15 p.m. ET, ESPN), they will be looking to stay in the AFC West race early against their archrivals.

Kansas City is coming off an impressive road victory over Tampa Bay, while Las Vegas beat Denver for its first win of the season in Week 4. Patrick Mahomes has been terrific as a strong MVP candidate passing for the Chiefs, while Derek Carr has struggled in the new Raiders offense under Josh McDaniels.

What will happen in the latest edition of the long-time matchup?

Here's everything to know about betting on Raiders vs. Chiefs in Week 5, including updated odds, trends and our prediction for "Monday Night Football."

Three trends to know

53 percent of the spread bettors are liking the Chiefs to take care of the comfortable number at home.

A whopping 75 percent of total bettors are easily taking the over despite the big number there.

The Raiders are 1-3 against the spread this season after going 8-10 ATS last season. The Chiefs are 2-2 against the spread this season after going 10-10 ATS last season.